Declining testosterone levels in men not part of normal aging

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Boston Testosterone Partners – A new study finds that a drop in testosterone levels over time is more likely to result from a man’s behavioral and health changes than by aging.

“Declining testosterone levels are not an inevitable part of the aging process, as many people think,” said study co-author Gary Wittert, MD, professor of medicine at the University of Adelaide in Adelaide, Australia. “Testosterone changes are largely explained by smoking behavior and changes in health status, particularly obesity and depression.”

Many older men have low levels of the sex hormone testosterone, but the cause is not known. Few population-based studies have tracked changes in testosterone levels among the same men over time, as their study did, Wittert said.

In this study, supported by the National Health and Medical Research Council of Australia, the authors analyzed testosterone measurements in more than 1,500 men who had measurements taken at two clinic visits five years apart. All blood testosterone samples underwent testing at the same time for each time point, according to Wittert.

After the researchers excluded from the analysis any men who had abnormal lab values or who were taking medications or had medical conditions known to affect hormones, they included 1,382 men in the data analysis. Men ranged in age from 35 to 80 years, with an average age of 54.

On average, testosterone levels did not decline significantly over five years; rather, they decreased less than 1 percent each year, the authors reported. However, when the investigators analyzed the data by subgroups, they found that certain factors were linked to lower testosterone levels at five years than at the beginning of the study.

“Men who had declines in testosterone were more likely to be those who became obese, had stopped smoking or were depressed at either clinic visit,” Wittert said. “While stopping smoking may be a cause of a slight decrease in testosterone, the benefit of quitting smoking is huge.”

Past research has linked depression and low testosterone. This hormone is important for many bodily functions, including maintaining a healthy body composition, fertility and sex drive. “It is critical that doctors understand that declining testosterone levels are not a natural part of aging and that they are most likely due to health-related behaviors or health status itself,” he said.

Unmarried men in the study had greater testosterone reductions than did married men. Wittert attributed this finding to past research showing that married men tend to be healthier and happier than unmarried men. “Also, regular sexual activity tends to increase testosterone,” he explained.

Source: The Endocrine Society

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances.  With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women.  Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

Boston Testosterone Partners

855.617.MEDS (6337)

Boston Testosterone Doctors – Testosterone Does Not Cause Prostate Cancer

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Boston Testosterone Partners

As leading Harvard Medical Doctors have been telling us for years, Testosterone Replacement Therapy does not cause cancer.

Men who undergo testosterone replacement therapy due to a drop in testosterone levels might not be at an increased risk of getting prostate cancer as previously thought, a new study from the U.K. suggests.

Researchers looked at nearly 1,400 men receiving testosterone replacement therapy for up to 20 years, and found that 14 cases of prostate cancer developed over the study period.

That number equates to one prostate cancer diagnosis yearly per 212 men; in the general population of U.K. men between ages 65 and 69, rates have been reported to be slightly less than one in 200 per year.

“This myth about testosterone replacement therapy being linked to prostate cancer has been rooted deep in medical consciousness for over 60 years,” said study co-author, Dr. Malcolm Carruthers, medical director at the Center for Men’s Health in London. “But this paper says no, testosterone treatment is actually good for the prostate, not bad.”

The study was published online June 6 in the Journal of Sexual Medicine.


Aging men sometimes experience “andropause”

Testosterone Levels vary greatly among men, but generally tend to drop with aging, sometimes causing them to experience a so-called “andropause.”

But unlike female menopause, which happens to all women as they age, not all men lose testosterone as they age, and the condition can also be overlooked, since the drop in hormone is gradual.  

According to the Mayo Clinic, however, by age 70, a man’s testosterone level can drop by as much as 50 percent.

With the drop, men can experience a number of symptoms, including reduced sexual desire, fatigue, depression, bone loss and increased body fat.

Testosterone replacement therapy can reverse these symptoms.

“Evidence is rapidly accumulating that, not only is testosterone treatment important in maintaining a man’s vitality and virility over the age of 50,” Carruthers said, “but also in the treatment of a wider range of serious physical and mental illnesses.”

But that may not always be the case when it comes to men who have already been treated for prostate cancer, according to Dr. Paul Nguyen, a radiation oncologist at Dana-Farber Cancer Institute in Boston.

“About 230,000 men a year are diagnosed with prostate cancer, and for those who have low testosterone after treatment, whether it’s safe to treat them with testosterone remains a big issue,” he said.

Testosterone treatment could improve quality of life

Researchers looked at 1,365 men participating in the ongoing U.K. Androgen Study. The men were treated with testosterone for at least three months for up to 20 years.

The researchers calculated that for every 10 men taking testosterone for 21 years, one would develop prostate cancer. In most cases, the cancer was detected with a test of prostate-specific antigen (PSA), a protein that suggests the presence of prostate cancer when found at high levels.

Based on study results, the researchers said that testosterone treatment is safe when carefully monitored.

As always, a larger study with longer follow-up would make doctors feel even more confident, Nguyen said. But he added the study was reassuring because of its size.

“For people with low testosterone who are thinking about getting treatment, this study helps to reduce the concern,” Nguyen said.

“So, it gives them the freedom to pursue this treatment, which can improve their quality of life.”

Pass it on: Testosterone treatment may not increase risk of prostate cancer.

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances.  With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women.  Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.


“The Greatest Health of Your Life” ℠  

Boston Testosterone Partners

855.617.MEDS (6337)

By Linda Thrasybule, My Health News Daily

Men With Low Testosterone Not Receiving Treatment

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Study finds patients with deficiency more likely to be poorer and without insurance 

Boston Testosterone Partners, Men’s Health Clinic. 

Boston, Massachusetts –  (HealthDay News) — Many men with low testosterone levels don’t receive treatment, even though they have access to care, according to a U.S. study. The study, which received funding from drug maker GlaxoSmithKline, was published in the May 26 issue of the journal Archives of Internal Medicine. 

The research involved 97 Boston-area men with the low testosterone, also known as androgen deficiency. Only 11 were prescribed treatment. Treatments included: testosterone gel (one patient); testosterone patch (three patients); testosterone cream (one patient); an injectable form of testosterone called testosterone cypionate (one patient); and unspecified formulations of testosterone (five patients). 

“All of the unspecified forms of testosterone used were self-reported as administered in intervals defined in weeks, which suggests that these were injectable formulations,” wrote Susan A. Hall, of New England Research Institutes in Watertown, Mass., and colleagues. 

Men with untreated androgen deficiency were most likely to have low socioeconomic status, no health insurance and to rely on an emergency department or hospital outpatient clinic for primary care, the study authors said. 

They also found that all men with androgen deficiency (treated and untreated) were more likely than men without the condition to report receiving regular care and visiting their doctor more often — 15.1 visits per year for those with untreated androgen deficiency, 12 visits for those with treated androgen deficiency, and 6.7 visits for those without the condition. 

“Under our assumptions, a large majority (87.8 percent) of 97 men … with androgen deficiency were not receiving treatment despite adequate access to care. The reasons for this are unknown but could be due to unrecognized androgen deficiency or unwillingness to prescribe testosterone therapy,” the study authors wrote. 

Symptoms of androgen deficiency include low libido, erectile dysfunction, osteoporosis, sleep disturbance, depressed mood and tiredness.

US News and World Reports 

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