Do Cholesterol Drugs Have Men By Their Gonads?

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Cholesterol-lowering agents in the statin drug class have long been linked with erectile dysfunction and low testosterone — effects that compromise more than just a man’s general sense of well-being and physical health, but his ego as well.

Now, a new study on statins and male fertility has found for the first time that this cholesterol-lowering class of drugs may be causing significant and lasting damage to men’s testicles and sperm, and by implication, possibly the health of future generations.

The new study published in Reproductive Biology and Endocrinology titled, “Evaluation of atorvastatin efficacy and toxicity on spermatozoa, accessory glands and gonadal hormones of healthy men: a pilot prospective clinical trial,” evaluated the effects of 10 mg daily of Lipitor (atorvastatin), daily, for 5 months, in 17 normal men with normal plasma lipid and standard semen parameters.

Sperm health parameters, accessory gland markers, semen lipid levels and blood levels of testicular hormones were evaluated before Lipitor intake, during the treatment, and 3 months after its withdrawal.

The alarming results were reported as follows:

  • Atorvastatin treatment significantly decreased circulating low-density lipoprotein cholesterol (LDL-C) and total cholesterol concentrations by 42% and 24% (p < 0.0001) respectively, and reached the efficacy objective of the protocol.”
  • “During atorvastatin therapy and/or 3 months after its withdrawal numerous semen parameters were significantly modified, such as total number of spermatozoa (-31%, p < 0.05), vitality (-9.5%, p < 0.05), total motility (+7.5%, p < 0.05), morphology (head, neck and midpiece abnormalities, p < 0.05), and the kinetics of acrosome reaction (p < 0.05). Seminal concentrations of acid phosphatases (p < 0.01), alpha-glucosidase (p < 0.05) and L-carnitine (p < 0.05) were also decreased during the therapy, indicating an alteration of prostatic and epididymal functions.”
  • “Moreover, we measured at least one altered semen parameter in 35% of the subjects during atorvastatin treatment, and in 65% of the subjects after withdrawal, which led us to consider that atorvastatin is unsafe in the context of our study.”

They concluded:

“Our results show for the first time that atorvastatin [trade name Lipitor] significantly affects the sperm parameters and the seminal fluid composition of healthy men.”

Why Are We Taking Statin Drugs If They Harm The Heart?

Statin drugs are purported to have cardioprotective properties because they reduce the production of low-density lipoprotein (LDL) – colloquially known as, and falsely equated with, ‘cholesterol‘ (there are actually hundreds of lipid species in the human liposome) – despite the fact the drug class itself has been found to be cardiotoxic to the heart muscle in several ways:

On the Statin Research database we have cataloged over 15 studies from the National Library of Medicine indicating the heart-damaging properties of this class of supposedly ‘heart friendly’ drugs.  View our professional data page here, or if you are not a member, view the open access reference page for public view and linking here.

Statins do not only reduce lipoprotein production but have so-called pleoitropic properties, which include immune system down-regulating and anti-inflammatory properties, which is why they are believed to have a small benefit in reducing the inflammatory burden caused by autoimmune processes in the artery that can precipitate myocardial infarction (heart attack) in some individuals — but not without having the unintended, adverse effect of increasing cancer risk (at all sites) and contributing to congestive heart failure, effectively cancelling out the small, mostly theoretical benefit of reduced heart attack risk. For instance, it has been estimated that “…at least 23,000 low-risk people would have to take statins for five years to prevent one death from heart disease.” [Source]

Statins are also clearly diabetogenic, increasing the risk of type 2 diabetes by about 50% in some populations, with the FDA now requiring drug manufacturers to include a warning of diabetes risk on statin drug labels. Considering morbidity and mortality from type 2 diabetes is caused not by the elevated blood sugar in and of itself, but the damage glycated sugar does to the vascular system and the subsequent cardiovascular harm it produces, the case against using statins for primary and secondary prevention of heart disease seems clear as day.

Moreover, cardiovascular harm is not the only concern. Statin drugs have been linked to over 300 adverse health effects. We issued a consumer alert on the topic several years ago. For the more technically minded, here is the database page on Statin drugs listing 300+ adverse health effects based on 465 published studies.

Heart Disease Is Not Caused By A Lack of A Drug

Should we be surprised to find so much research on this drug class’s adverse health effects? After all, cholesterol is fundamental for the health of each cell in the human body, and low cholesterol has been found to cause a wide range of health problems, including psychiatric states such as violence against self and other. The food and drug industries have used cholesterol phobia to manipulate health professionals and the lay public into believing that the cause of heart disease is genetic, and can only be addressed through the use of synthetic, patented, essentially toxic chemicals, i.e. pharmaceuticals, or eating semi-synthetic ‘low fat,’ ‘low cholesterol’ foods with very little nutritional value.

This latest study speaks to why we must exercise the precautionary principle when considering taking a patented chemical – technically a xenobiotic alien to human physiology – for suppressing a symptom of a much deeper and more complex problem. While oxidized cholesterol forms a significant part of the problem of atherosclerotic build-up in the arteries, it is not the primary cause of the damage to the inner lining of the arteries (endothelium), and the pre-existing endothelial dysfunction that can go on for many decades silently in the background. Ox-LDL deposits in atheromatous lesions have been viewed as an epiphenomenon, generated as part of a cascade of immune-mediated events the body activates in order to attempt to heal arterial damage. In certain respects, cholesterol deposits in the arteries at the site of damage can be likened to a Band-Aid. Do we blame the Band-Aid for causing the injury upon which it is placed?

It is important to point out that oxidized cholesterol (ox-LDL) can be toxic and harmful to the vascular system, but the problem with modern blood testing for ‘cholesterol’ is that it does not take into the quality of the lipoproteins, only their quantitative dimensions.  Depending on one’s diet, environmental factors, and overall bodily health, LDL particles will oxidize at different rates. If you are eating an antioxidant rich diet, full of healthy fats, phytocompounds, etc., your properly functioning LDL will be less susceptible to conversion to ox-LDL.  On the other hand, eating a diet full of non-essential, oxidized fats, deficient in phytonutrients, antioxidants, etc. – and adding in environmental toxins and toxicants, e.g. smoking – will produce more ox-LDL, rendering it artherogenic. Obviously, therefore, diet and lifestyle form the basis for a sound preventive approach if the ‘lipid hypothesis‘ of cardiovascular disease is even deemed truly relevant. [For more research on natural substances which inhibit cholesterol oxidation, view our database on the topic: Prevent Cholesterol Oxidation.]

Furthermore, there are many ways to address underlying vascular pathologies without suppressing the production of a vital building block and signaling molecule, which is what cholesterol is. Pomegranate, chocolate, and many other natural substances, have been confirmed in research to have profound heart disease preventive and reversing properties. You can explore our database sections relevant to the topic within our Heart Health guide, to find hundreds of studies proving this point. Basic nutritional incompatibilities, including the consumption of wheat which has cardiotoxic properties in genetically susceptible individuals, and excessive consumption of omega-6 versus omega-3 fats can profoundly increase the risk of heart disease. One groundbreaking study published last year, in fact, indicates that statins actually reduce the health benefits of omega-3 fats in the diet – adding another mechanism by which statin drugs exert heart disease promoting effects.

Beyond the Pharmaceutically-Driven Medical Paradigm

If statin drugs are toxic to human sperm, and if the men within whom this statin-induced damage is occurring are of reproductive age, the implications of this latest study on statins and fertility are potentially devastating to the health of future generations. Changes in our species germlines – sperm or egg – are carried on to future generations, possibly forever. With recent research indicating that even changes to somatic cells in this lifetime are capable of transferring information to the sperm, what we do here and now – our chemical exposures, our nutritional status, and even our psychospiritual and mental orientation (which gear into real physiological and genetic/epigenetic processes – can have critical and irreversible affects on our offspring.

Clearly, the time has come both to re-evaluate the role of pharmaceuticals in ‘preventive’ health care, as well as the effects these novel new chemical compounds will have on the next generation, and the next.

For alternatives to lipid lowering chemicals, take a look at the following, evidence-based natural interventions:


For more information and appointments, please contact Clinic Director Charlie Blaisdell at

BTP/CORE New England
Clinic: 781-269-5953

What a Man’s Testicles Tell About His Health

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It’s commonly known that we studs often think about s*x. We like talking about what turns us on. Still, concerns about our boys are kept in the closet. There are several important facts that shouldn’t be kept under wraps. Here we disclose what every man should know about his nuts.



Your balls consist of three structures:

testicles – oval-shaped organs that manufacture testosterone. This chemical messenger regulates:

  • s*x drive
  • sperm production
  • red blood cell formation
  • muscle size and strength
  • bone mass
  • fat distribution

epididymis – a tube on the back of each testicle that stores and transports sperm.

scrotum – a loose sac of skin that holds and protects your testicles.

Here’s a diagram of your manly equipment.


Testicles average two inches in length and one inch across. It’s normal for your nuts to be mismatched in size. If one sits lower and behind the other, that’s fine. It’s actually a divine design. It keeps your balls from bashing together. In most guys, the right ball is slightly larger, and the left is positioned lower. Testicles should feel smooth and firm but not hard.

The location of your balls outside your body is also ingenious. It creates the ideal climate for sperm incubation, two degrees below internal body temp.


Testicles can serve as crystal balls. Research shows they can indicate:

  • heart health
  • sleep quality
  • fatherly inclination


Large balls may foretell heart disease. A 2013 Italian study reported in the Journal of Sexual Medicineevaluated 2,800 men. Testicle size and hormones were measured over a seven-year period. Men with large testicles had a greater incidence of high blood pressure and cardiac complications.

The link between heart disease and testicle size appears to be luteinizing hormone (LH). This chemical is released by the pituitary gland and triggers testosterone production. A high LH level raises the risk of a blood clot, stroke, or heart attack. If your testicles are growing larger, it’s time to see your doctor.


A 2012 Danish study found a connection between small avocados and poor slumber. Scientists surveyed nearly 1,000 men regarding their sleep habits, followed by measuring sperm count and testicle size. Men who were sleep-deprived had 29 percent lower sperm counts than men who slept soundly. They also had smaller balls.


According to Emory University research, guys with small balls are more likely to be doting dads than men with sizable genitals. The study evaluated 70 American men who were fathers of a toddler. Those with small family jewels were more involved with feeding, diapering, and bathing. MRI scans also showed increased brain activity in areas associated with parental motivation. The study was published in the Proceedings of the National Academy of Science.


Trauma to your walnuts can have serious consequences. Testicles lack the protective muscles and bones that most organs have. A prolonged squeeze can trigger a sudden drop in blood pressure and cause fainting. A hard hit can make you sterile.


If you’re looking to become a father, here’s how to keep your family jewels in baby-making shape. Increase your antioxidant intake. Avoid smoking and alcohol. Smoking kills your swimmers, lowering sperm count. Alcohol can reduce testosterone, impair sperm production, and cause erectile dysfunction.

Healthy foods that increase sperm production are:

  • bananas, strawberries, oranges, cherries
  • dark chocolate
  • walnuts
  • spinach
  • eggs

Also, avoid wearing tight underwear, pants, or bathing suits. If you play contact sports, be sure to wear a protective cup. If you bicycle, choose a saddle that accommodates your coconuts.


For your jewels to produce sperm, the environment must be just right. Temperature regulation is your scrotum’s responsibility. It changes size to maintain swimmer viability. When you’re cold, your scrotum shrinks to conserve warmth. When you’re hot, it relaxes to release the extra heat.


Swollen testicles can be caused by:

  • Hydrocele – a fluid collection around a testicle. The cyst may be uncomfortable but typically isn’t painful or dangerous. A hydrocele can result from scrotal injury or inflammation. Treatment usually isn’t necessary. A doctor may recommend hydrocele repair if a cyst becomes too large, infected, painful, or interferes with blood flow.
  • Infection – resulting from a virus or sexually transmitted disease.
  • Inguinal Hernia – a condition where part of the intestine pushes into the scrotum or groin through a weak area of the abdominal wall.
  • Varicocele – venous swelling.
  • Testicular Trauma – such as being hit, kicked, squeezed, or crushed.
  • Torsion – twisting of a testicle. This is an emergency, requiring immediate medical attention.
  • Cancer – see next section.

Any sign of swelling should be examined by your doctor. 8/


The odds of a man getting testicular cancer are roughly 1 in 270. It’s the most common form of carcinoma in young and middle-aged men. When diagnosed early, testicular cancer has a 96 percent success rate. Even if cancer has spread, up to 80 percent of cases can be cured.


In many cases, the cause of testicular cancer may not be clear. However, there are risk factors that can predispose you to develop carcinoma. These are:

  • Undescended Testicles – balls form in the abdomen during fetal development. Usually, they descend into the scrotum before birth. If testicles don’t comply with the plan, this increases cancer risk. Even if testicles are surgically relocated to the scrotum, the risk remains.
  • Abnormal Development – Klinefelter syndrome is a common genetic male abnormality. It delays testicular growth, resulting in smaller than normal testicles. It can also cause enlarged breast tissue, weak muscles, and sparse body and facial hair.
  • Family History – testicular cancer in family members increases the odds.
  • Age – Men between the ages of 15-35 are at increased risk.
  • Race – Testicular tumors are more common in Caucasian versus African-American men.

NOTE – Many men who develop testicular cancer have no risk factors.

Red Flags

Self-examination should be performed at least once monthly after bathing. Cancer usually affects one testicle. According to the Mayo Clinic, here are the signs to watch for:

  • testicular swelling or enlargement
  • hardening
  • lumps
  • significant reduction in size
  • scrotal heaviness
  • a dull ache in the groin, abdomen, or back
  • a sudden collection of fluid in the scrotum
  • testicular or scrotal pain
  • breast tissue enlargement or tenderness

Testicular Examination

Self-examination can save your life. Here’s how to check for suspicious signs:

1. Do your assessment right after a warm bath or shower, when the scrotum is relaxed.

2. Stand before a mirror. Survey for scrotal swelling.

3. Support your testicles with your palm. Note their size and weight. This will help you discern any future changes.

4. Examine each testicle separately. Place your second and third fingers under one testicle with your thumb on top. Gently roll the testicle between your thumb and fingers to feel for any irregularities. Repeat on the other testicle.

5. Find the epididymis, the soft, rope-like structure on the back of each testicle. By identifying the epididymis, you won’t mistake it for a lump.

See your doctor if you note any questionable signs, especially those lasting longer than two weeks.


Now you’re a coconut crackerjack. You know all about:

  • size and location
  • heart health
  • sleep quality
  • fatherly inclination
  • protecting your jewels
  • fertility
  • shrinkage and expansion
  • swelling
  • cancer

So, fellow hunks and stud muffins, may you each live long and prosper!


“The Greatest Health of Your Life” ℠

Boston Testosterone Partners

855.617.MEDS (6337)

Is Male Menopause Real?

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If you have any of these symptoms or know anyone who does, please check out our website and give us a call to find out what you can do.

Is Male Menopause Real? 

By Daniel D. Federman, M.D., and Geoffrey A. Walford, M.D.

Newsweek Jan. 15, 2007 issue – You’re a guy in your late 50s. You’ve just awakened and are looking at yourself in the bathroom mirror—as you do every morning. Only today you notice for the first time what must have been there for a while: the love handles, the once bulging pecs that now sort of sag. It gets you thinking. You realize that for some time you haven’t had as much energy as you used to, you don’t have as much interest in sex, there are times when you feel down and discouraged, and your friends tell you that you’re more irritable than you used to be. Is this just aging? Is it simply the inevitable price of your nutritionally rich and exercise-poor lifestyle? Or is it a medical condition—one for which there might be a treatment?

Are you entering “male menopause”? You’ve heard the phrase, but is there really such a thing?

Like women, men experience a drop in the levels of sex hormones as they age. But in men, the pace of these changes is quite different. In women, levels of the main female sex hormone, estrogen, remain high for most of their adult lives, and then, around the age of 50, plunge over the course of five years. The lower levels of estrogen cause the physical and psychological changes of menopause, including the most obvious one: the cessation of menstrual periods. When a woman has entered menopause, it’s not hard for her to tell.

With men, it’s much more gradual. Levels of a man’s main sex hormone, testosterone, begin to drop as early as the age of 30. Instead of plunging over a few years, the testosterone levels drop very slightly (about 1 percent) each year—for the rest of his life. This change is so gradual that many men may not notice any effects until several decades have gone by. Yet, by 50, 10 percent of all U.S. men have low levels of testosterone. By 70, more than half are testosterone deficient.

Do the progressively lower levels of testosterone cause symptoms in a man, the way lower levels of estrogen do in a woman? There is no doubt that they can, but it can be very hard to tell. Men with certain rare conditions that cause extremely low levels of testosterone develop a loss of muscle mass and bone strength, increased body fat, decreased energy, less interest in sex, erectile dysfunction, irritability and depression. In men with these rare conditions, testosterone-replacement therapy can improve their symptoms.

In the average man, however, linking testosterone levels to symptoms and predicting which men with low levels will benefit from treatment is tricky, for several reasons. First, there are many conditions that can cause the symptoms associated with testosterone deficiency. Alcohol abuse, thyroid and other hormonal disorders, liver and kidney disease, heart failure and chronic lung disease can all cause similar symptoms. Depression can cause many of these symptoms in men with perfectly normal levels of testosterone.

Second, some testosterone in the blood is “active” and other testosterone is inactive. It is low levels of active testosterone that cause symptoms of testosterone deficiency, yet doctors typically test just for “total” testosterone. Third, testosterone levels vary widely among men of the same age, including the majority of men without symptoms of testosterone deficiency. Fourth, testosterone levels fluctuate over the course of the day and vary widely among healthy men. For all those reasons, it’s difficult to determine what a “normal” level of testosterone is.

Perhaps most perplexing, men experience symptoms of testosterone deficiency at very different levels: some men with what appear to be low levels of active testosterone have no symptoms, and some men with what appear to be “normal” levels of active testosterone have symptoms that improve with testosterone therapy.

Despite these complexities, symptoms due to testosterone deficiency in men older than 50 definitely occur and can be diagnosed and treated. As many as 10 million U.S. men may be affected. As the baby-boomer generation ages over the next 25 years, this number is expected to rise significantly.

So what should you do if you have symptoms that could reflect a testosterone deficiency? If you are older than 50 and have symptoms, see your doctor. The doctor should first determine whether the symptoms may be caused by other conditions. If not, the doctor should measure blood levels of total testosterone. The tests should be done in the morning, when testosterone levels are the highest, and repeated at least once to ensure accuracy.

If your levels are greater than 400 nanograms per deciliter, you are not testosterone deficient, and the symptoms must have some other cause. If your total testosterone level is less than 200ng/dl, you are clearly deficient. If your levels are borderline—between 200ng/dl and 400ng/dl—you may be deficient; to be sure, you should have your active testosterone measured.

When can you benefit from testosterone therapy? If you have symptoms and extremely low levels of total or active testosterone, you will likely benefit. If you have borderline levels, however, the evidence is less clear: some studies show a benefit, others do not.

Is there a risk to testosterone treatments? In some patients, testosterone-replacement therapy (TRT) can cause or worsen sleep apnea. High levels of testosterone can raise the number of blood cells, increasing the risk of blood clots, heart attacks and stroke. The most significant concerns regarding TRT are potential effects on the prostate. Prostate growth and cancer are both testosterone-dependent. Increasing testosterone levels could theoretically lead to a greater incidence of enlarged prostates, also known as BPH, and to progression of prostate cancer. Although no short-term studies have shown an increased frequency of prostate cancer in men taking TRT, the long-term effects on the prostate are still unknown.

So, for many men with borderline levels of testosterone, the benefits and the risks of testosterone therapy are uncertain. Despite this, for the past 20 years many men have begun using testosterone supplements. In 2005, more than 2.3 million testosterone prescriptions were written—most of them for men between the ages of 50 and 65. Yet men older than 65 have a much greater likelihood of having significant testosterone deficiency. So it may be that testosterone supplements are being overused by men below 65 and underused by those over 65.

Many formulations of testosterone supplements are available today. In the United States, the most commonly used preparations are patches, gels and intramuscular injections. Patches and gels are easy to use and provide a constant, steady release of testosterone through the skin and into the blood. However, patches can cause skin irritation, and gels are slow to be absorbed and can leave a musty smell. Intramuscular injections have to be given in a health-care setting every two to four weeks, inconvenient for many men. Additionally, intramuscular preparations produce unnaturally high blood levels right after the injection, which over several weeks fall to unnaturally low levels. Indeed, some men experience a return of their symptoms before the next injection.

Testosterone pills were popular 20 years ago, and prompted the widespread use of testosterone supplements. However, they were found to cause liver damage and liver tumors, and were removed from the market. Since then, newer and safer testosterone pills have been developed and are available in Europe. Once appropriate safety tests have been done, it is likely that they will also become available in the United States. In addition, new hormones called selective androgen receptor modulators (SARMs), which resemble testosterone but do not affect the prostate, are under development. Theoretically, these SARMs could offer the benefits of conventional testosterone therapy and significantly decrease the potential harmful side effects of the therapy.

If your doctor has prescribed testosterone treatment, the dose should be determined by symptom relief. In addition, your doctor should regularly measure your testosterone levels—to ensure that they do not become too high, increasing the risk of dangerous side effects. Finally, you should have regular physical examinations and blood tests to monitor for potential damage to the liver, blood and prostate. Additionally, you and your partner should watch for symptoms of sleep apnea: unusual snoring and daytime sleepiness, and periods of 10 seconds or longer during sleep when you do not take a breath. Sleep apnea is a potentially life-threatening side effect of TRT.

Whether you call it “male menopause” or not, some men do develop serious and bothersome symptoms from testosterone deficiency. Unfortunately, medical science knows much less about male menopause than about female menopause. With the growing interest in this problem, and the likelihood that testosterone pills will re-appear in the United States, that knowledge gap is likely to shrink. Now, if only our prostates would do the same.

Federman and Walford are members of the faculty of Harvard Medical School. For more information on male menopause and men’s health, go to

For more information on our unique Men’s Testosterone and Wellness therapies visit us at or

“The Greatest Health of Your Life”℠
Boston Testosterone Partners
National Testosterone Restoration for Men
Wellness & Preventative Medicine
855-617-MEDS (6337)


Why You Don’t Need to Worry About Your Health Over the Holidays

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It’s the holidays and you’ve probably seen endless stories about how you can “stay healthy over the holidays” — tips intended to keep you from “overindulging.” Ick! It’s the holidays – and how un-fun is it to be at a party when your chief concern is avoiding the baked Brie? DELETE. Oh, and please pass the peanut butter haystacks.

As a doctor, I’m going to tell you to stop stressing. Not only do most of those deprivation-fueled tips not work (who writes those things anyway?), staying healthy without obsessing is much easier than you think. That’s mainly because there are likely things that you already enjoy — and don’t realize how good they are for you. Emphasize these four things and you won’t have to choose between celebrating and health after all:

1. Spending time with loved ones adds years to your life. Fact. Statistics in the RealAge Test show that having close connections with people and engaging with them regularly can add almost two years to your life; it also lowers your risk of heart disease and cancer. Think of the holidays as a time of seeing the people who brighten your life – rather than a series of diet-killing party obstacles — and you’ll come away with both a heart and soul that are healthier.

2. Be a kid again. When you were six, did you count calories? What’s a calorie? No! You were too busy running and playing and climbing trees to worry about it. Use the holidays as a time to let out your inner child – whether it’s playing with your own children (or relatives’ kids) when they’re on vacation – or just getting out and doing something you love. Extra bonus? You may eat fewer calories later. In one 2014 study from the Cornell Food and Brand Lab, participants were either told that they were going on a scenic walk or an exercise walk around a lake; afterwards they were served lunch. The ones who thought they were on a walk for fun ate 35% less desserts than those who were told they were doing it for exercise.

3. Allow yourself to indulge. Avoiding foods? Skipping meals to save calories for later? Both lead to eating more calories overall than you would have in the first place, meaning that not only are you miserable, but also less healthy (womp womp). Allow yourself a cheat meal (or cheat party) here or there, where you leave the food police at home, and you’ll find that staying on track the rest of the time seems far more doable.

4. Sing (or dance) along to your favorite holiday tunes. It doesn’t matter if it’s in your local choir, caroling with friends, or in your car – singing lowers levels of anxiety and depression, dancing extends your life and even may reduce your risk of Alzheimer’s disease . Even if you’re a little more Napoleon Dynamite than Flashdance, in the words of the venerated Meghan Trainor, “Prove to them you got the moves, I don’t know about you. But I feel better when I’m dancing.”

Indulging, dancing and hanging out with your best people — who knew it was healthy? Focus on them, and you’ll have a memorable holiday season that’s good for the heart — and the soul.

Happy holidays to you and your loved ones.
Very best,
Dr. Darria

This content originally appeared on

For more information and appointments, please contact Clinic Director Charlie Blaisdell at

BTP/CORE New England
Clinic: 781-269-5953

Low Testosterone levels in Men Linked to Whole Body Inflammation

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Low testosterone levels have been linked to a marker of whole body inflammation, C Reactive Protein.  When germs, high levels of fat in blood or high blood pressure are present they cause cellular injury, resulting in inflammation of the body.  Harboring inflammation over an extended period of time can lead to tissue destruction and a variety of health problems such as allergies, cancer, arthritis and autoimmune diseases.

A recent study has found a link that was very strong in overweight men as well as those with the risk factors of heart disease, such as low testosterone.  High blood pressure, obesity, diabetes, smoking and high blood fats were positively linked to increased C Reactive Protein, therefore inflammation.

Very importantly, higher levels of total testosterone (TT, β = −0·114, 95%CI, −0·162 to −0·065), free testosterone (β = −0·059, 95%CI, −0·106 to −0·012) and SHBG (β = −0·116, 95%CI, −0·169 to −0·063) were statistically significantly related to lower levels of C Reactive Protein  (Clinical Endocrinology, 78: 60-66, 2013).

The clinical studies surrounding the associated dangers of low testosterone (LOW T) in men are staggering.

If you are a man of 30 years of age and feel you may be suffering from Low Testosterone, Hypogonadism or Andropause, contact Boston Testosterone Partners today for a consult on how you can get tested.

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances.  With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women.  Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.


“The Greatest Health of Your Life” ℠

Boston Testosterone Partners

855.617.MEDS (6337)


Safety of Testosterone Therapy & Clueless Primary Care Physicians

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Boston, MA – Testosterone replacement therapy for hypogonadal men has been used for decades. However, there are still scores of primary care doctors spreading irresponsible misinformation regarding the safety of this treatment, particularly to elderly men who can benefit mightily from a balanced hormonal health.

A study was done with 255 men with an Average age of 60.6 ± 8.0 years, with testosterone levels between ≤ 3.5 ng/ml. They received parenteral (injectable) testosterone undecanoate.

After more than five years of monitored testosterone therapy, the study noted that a mere 3 out of 255 patients were diagnosed with prostate cancer.  The study stated that “3/255 patients with prostate cancer does not suggest an increased risk of prostate cancer in elderly men on long-term testosterone treatment.  Long-term treatment with testosterone undecanoate with monitoring according to the guidelines is acceptably safe.”

Now, according to, “About 1 man in 6 will be diagnosed with prostate cancer during his lifetime.”  They also stated, “Prostate cancer can be a serious disease, but most men diagnosed with prostate cancer do not die from it.  In fact, more than 2.5 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.”

In over 50 years of studies and research, there has never been a connection between testosterone levels in men and prostate cancer growth.  Moreover, a study from Harvard Medical School in 2006 concluded, “there is not now, nor has there ever been a scientific basis for the belief that testosterone causes prostate cancer to grow.”

Just more evidence that testosterone replacement therapy does not cause cancer or prostate cancer.  We can’t explain why leagues of completely clueless primary care doctors still spread baseless accusations that TRT is unsafe. … statistics

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances.  With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women.  Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

Boston Testosterone Partners

855.617.MEDS (6337)

See:  Side-Effect Profile of Long-Term Treatment of Elderly Hypogonadal Men with Testosterone Undecanoate  – Farid Saad, Ahmad Haider, Gheorghe Doros, Louis Gooren. Bayer Pharma AG, Berlin, Germany; Gulf Medical University School of Medicine, Ajman, United Arab Emirates; Private Practice, Bremerhaven, Germany; Public School of Health, Boston University, Boston, MA; VUMC Amsterdam, Amsterdam, Netherlands.

Boston Men Show Decline in Testosterone (Male Hormone) Levels

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A recently published study confirms what has been suspected for some time, which is that men in the Boston area over the past two decades are showing declining levels of testosterone (male hormone), in their blood. Over twenty years the average testosterone level in these men dropped from 501 to 391. Many experts regard a testosterone lower than 300 to be abnormally low and possibly needing testosterone replacement treatment. One of the scientists on the study, Dr. Thomas Travison states that when comparing testosterone levels in Boston men from 1987 to 2005 a decline in the testosterone level in every adult age group was found over this time. The researcher stated that the speed with which the levels of male hormone declined over the twenty years and the uniformity of the decline in all age groups was cause for concern.

It is known that testosterone levels decline slowly as men age. Declining male hormone levels were found even in the 45 to 71 year age range, however. Other known causes of declining testosterone levels, the growing incidence of obesity and sedentary life style in Boston men, did not explain the findings, say the researchers.

Could other factors be at work here? Alcohol has a powerful effect on male hormone levels for many reasons. Some alcohol products like bourbon and beer may have estrogen (female hormone) like plant products in them. Liver disease from excess alcohol consumption can also reduce the level of male hormone. Other drugs may have a negative effect on male hormone production such as cannabis (marijuana, Mary Jane, pot, herb, weed, splif, ganja, the bomb, the shit etc.). Although not nearly as wide spread in its use are the opiate type drugs, heroine, methadone, opium, codeine, hydrocodone etc. which can severely depress male hormone levels.

Environmental pollutants are known to cause adverse hormonal effects in men. Pollutants such as PCB’s and DDT act like female hormone and could reduce a man’s testicular function (the testicle is the site of testosterone and sperm production in men). Even herbal products can have anti-male hormone effect such as soy, black cohosh, and white clover. Perhaps the Boston men are being exposed to these influences more now then in the past and the result is sinking male hormone levels.

Before concluding that Boston men are simply pot smoking, beer drinking, soy eating effeminate couch potatoes, the authors of the recent study call for additional research into the possible origins of this serious loss of virility hormone in the Boston area.

Gary Pepper M.D.

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