New skin patch device analyzes sweat during physical activity

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A new skin patch device has been created for analyzing sweat during exercise. The results collected from the patch are then sent to a smartphone. This information offers a valuable insight into the person’s state of health, for example, whether they require more hydration or whether their electrolyte levels are balanced.

Lead author of the study John Rogers explained, “The intimate skin interface created by this wearable, skin-like … system enables new measurement capabilities not possible with the kinds of absorbent pads and sponges currently used in sweat collection.”

The disposable skin patch is made for one-time use for several hours. It can be placed on the forearm or on the back.

You may be wondering why you should have your sweat analyzed. As Rogers explained, it offers “a rich, chemical broth containing a number of important chemical compounds with physiological health information.”

Written By:  Emily Lunardo

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Long-Term Metformin Use Linked with Vitamin B12 Deficiency

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Long-term use of the popular diabetes drug metformin is linked with vitamin B12 deficiency and anemia, according to new research that solidifies some previous research.

“We have essentially confirmed what many smaller studies have suggested,” says Jill Crandall, MD, professor of clinical medicine at the Albert Einstein College of Medicine, the Bronx, who led the new study. “There is a small but significant risk of developing Vitamin B12 deficiency when people take metformin.”

The finding, she adds, ”has implications for the consequences of B12 deficiency.” These can include cognitive impairment, nerve problems (neuropathy) and anemia (low red blood cell count). B12 is crucial for the proper formation of red blood cells, for neurological functioning and for making DNA.

The link between taking the popular diabetes drug and deficiencies in vitamin B12 has been discussed as long ago as 1969, according to Dr. Crandall. However, few studies have looked at long term use, as her new study has done, tracking people for up to 13 years.

The new study was published online Feb. 22 in the Journal of Clinical Endocrinology & Metabolism.

Overview of the Metformin Study

The researchers evaluated more than 2,000 men and women enrolled in the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study. In these studies, researchers enrolled overweight people who had prediabetes (blood sugar levels higher than normal but not high enough to be termed diabetes) to see if modest weight loss or treatment with metformin could prevent or delay the onset of type 2 diabetes, then followed them to see if the effects endured.

Half of the participants were given 850 milligrams of metformin twice daily and half got placebo pills. At the 5-year mark, more of those in the metformin group than the placebo group had low B12 levels, affecting 4.3% of the metformin group but just 2.3% of the placebo group. However, the gap narrowed at 13 years, with 7.4% of the metformin group and 5.4% of the placebo group having low B12 at that point. The narrowed gap seems counter-intuitive until Dr. Crandall explains what is happening.  “As time goes on, the groups are a little contaminated,” Dr. Crandall says, because some in the placebo group, as time went on, developed diabetes and had to begin taking metformin.

Years of use was linked with an increased risk of B12 deficiency, Dr. Crandall found. Those taking metformin were more likely to have anemia, regardless of their B12 status. Those taking metformin with low B12 were more likely to have neuropathy.

The study findings suggest that routine testing of Vitamin B12 should be considered in patients on metformin treatment, Dr. Crandall says. Experts think that metformin affects the way Vitamin B12 is absorbed by the body. “People should be aware of this possibility,” Dr. Crandall says of the metformin and low B12 link. Currently, she says, there are no official recommendations for B12 testing of those on metformin.

Metformin & Vitamin B12: Second Opinion

“I think it lends more support to a practice that is already in place with endocrinologists,” says Minisha Sood, MD, director of inpatient diabetes at the Lenox Hill Hospital, New York, of the study findings. She reviewed the research but didn’t participate in it.

She screens for Vitamin B12 deficiency in her patients ”at least annually if on metformin.”  According to Dr. Sood, many endocrinologists do screen for B12 deficiencies in those on metformin. However, she says, many patients with diabetes who are on metformin are cared for by general practice physicians or internists. These patients should ask their doctor’s advice about getting screened for B12 deficiencies, Dr. Sood says.

B12 Deficiency Symptoms & Treatment 

Symptoms of B12 deficiency may include numbness, tingling in the feet, and memory problems, Dr. Crandall says. Loss of appetite, weight loss and fatigue can occur. The deficiency typically develops slowly over time, so the regular screening could detect it early.

Treatment includes a weekly B12 injection and then switching to oral vitamins.

The recommended dietary allowance (RDA) for B12 is 2.4 micrograms for those age 14 and older.  Foods high in B12 include cooked clams and beef liver, fortified breakfast cereals and fish such as salmon and trout.

Written by: Kathleen Doheny  With commentary by Jill Crandall, MD, professor of clinical medicine, Albert Einstein College of Medicine, New York.

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Low DHEA Predicts Coronary Heart Disease

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Men with low blood levels of DHEA may be at increased risk of developing coronary heart disease events.

The most abundant steroid in the human body, dehydroepiandrosterone (DHEA) is involved in the manufacture of testosterone, estrogen, progesterone, and corticosterone.  Claes Ohlsson, from Sahlgrenska Academy (Sweden), and colleagues monitored 2,614 men, ages 69 to 80 years, who resided in 3 Swedish communities, for five years, during which DHEA levels were assessed. The findings demonstrated that the lower the DHEA level at the study start, the greater the risk of coronary heart disease events during the five-year follow-up.  The study authors report that: “Low serum levels of DHEA and its sulfate predict an increased risk of [coronary heart disease], but not [cerebrovascular disease], events in elderly men.”

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Solutions for Common Prostate Problems

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By the time men reach their 50s or 60s, it is almost inevitable that they will experience difficulties related to their prostate gland.

Common symptoms include more frequent need to urinate, waking up during the night to “go,” or trouble even “going” at all.

These signs should not be ignored or overlooked as they can indicate serious problems, including benign prostatic hyperplasia (BPH), prostatitis, and even prostate cancer.

Fortunately, a number of natural extracts have proven value in preventing, and often reversing, symptoms of benign prostatic hyperplasia and chronic prostatitis with a high safety profile.

There is also evidence that certain supplements can help prevent prostate cancer, and even slow the rate of cancer progression if it does occur.

This article supplies essential information for men wishing to prevent prostate trouble—and solutions for those with existing issues.

The Aging Prostate Gland

The three most common prostate conditions are:
  1. Benign prostatic hyperplasia
  2. Prostatitis (inflammation of prostate)
  3. Prostate cancer1

These conditions often produce similar symptoms in their early stages, making it difficult to differentiate between them. These common symptoms can include the following:

  • More frequent need to urinate
  • More urgent need to urinate
  • Decreased urine flow or dribbling
  • Frequent nighttime awakening to urinate
  • Burning with urination

The reason prostate problems are likely to cause trouble with the lower urinary tract has to do with the prostate’s location. The prostate is located between the lower part of the bladder and the rectum. It surrounds the internal part of the urethra, the tube that carries urine from the bladder to the end of the penis.

When the prostate swells, whether because of benign prostatic hyperplasia, prostate cancer, or prostatitis, it narrows the urethra, making it difficult for urine to pass freely from the bladder. As the gland continues to grow, it can produce sufficient blockage to lead to difficulty urinating, and even urinary retention, which in turn can result in bladder and kidney infections.

While most prostate problems can be readily treated—and the vast majority are not cancer-related—it is important to seek medical attention as soon as a symptom arises.1

Researchers have identified a number of nutrients that have been found to alleviate many of the unpleasant prostate symptoms. Let’s look at the data on some of the best-known and most effective supplements that can help men optimize their prostate health.

Nature’s Solutions for Benign Prostatic Hyperplasia

Benign prostatic hyperplasia is an enlargement of the prostate gland. Approximately 25% of men in their 40s have benign prostatic hyperplasia, with a startling 80% of men in their 70s suffering from the condition.2

The good news is that benign prostatic hyperplasia (BPH) is not cancerous. It is a major risk factor for sexual dysfunction. Conventional treatments for benign prostatic hyperplasia can cause unpleasant side effects that are also a cause for sexual dysfunction.3

Fortunately, studies have shown that certain nutrients help alleviate many of the symptoms associated with benign prostatic hyperplasia and can significantly improve quality of life as a result.

Saw Palmetto

Saw palmetto is one of the most well-known natural treatments for prostate problems. Recent studies suggest that saw palmetto may also be beneficial for chronic prostatitis, prevention of prostate cancer, and even sexual dysfunction.3,4

There is evidence to suggest that saw palmetto has similar efficacy to finasteride (Proscar®) and tamsulosin (Flomax®), two medications used to treat benign prostatic hyperplasia.3,5,6 Of even greater interest, a lower incidence of associated sexual dysfunction was seen in men supplemented with saw palmetto compared to those given pharmaceuticals.5

A 2013 study demonstrated that elderly men treated with 320 mg of saw palmetto extract daily for eight weeks not only experienced a significant 52% improvement in their International Prostate Symptom Score (IPSS), the standard tool used to measure the severity of benign prostatic hyperplasia symptoms, but also had a significant 40% improvement in sexual dysfunction scores!3

A host of other studies compellingly demonstrate the impact of saw palmetto extract on symptoms of benign prostatic hyperplasia. Two large meta-analyses including more than 7,000 men from 38 studies showed that saw palmetto extracts produced significant improvements in the International Prostate Symptom Score, reductions in frequency of nighttime urinations, and improvements in peak urine flow rates.7,8 Indeed, saw palmetto produced similar improvements in urinary symptoms and urinary flow compared to the drug finasteride, but with fewer adverse effects.7

Based on all of these studies, a 2015 review article concluded that, while drug therapy might be most effective for moderate to severe benign prostatic hyperplasia, herbal medications including saw palmetto are useful for men with mild to moderate symptoms.9

Not all studies demonstrate desired relief with saw palmetto,10 which is why combining it with additional nutrients is the preferred choice for most aging males.


Natural Treatments for Prostate Health

  • The prostate is a walnut-sized gland that has important functions in the male reproductive system.
  • With age, the prostate is known for causing problems with urination and pain, as well as cancer.
  • A number of natural extracts have proven value in preventing and often reversing symptoms of benign prostatic hyperplasia and chronic prostatitis as effectively and with a much better safety profile than existing drug therapies.
  • Most prostate problems are not cancer-related, and proper supplementation can lead to improved prostate health and fewer risks for problems down the line.

Stinging Nettle Root

Stinging nettle root (Urtica dioica) has been widely used as therapy for benign prostatic hyperplasia.11 Both human and animal studies have shown that nettle root extract is effective not only in relieving benign prostatic hyperplasia symptoms, but also in shrinking the size of the prostate gland.11-13

A study on nettle root extract was shown to improve lower urinary tract symptoms significantly better than placebo, with marked improvements in the International Prostate Symptom Scores, increases in peak urinary flow rates, and reductions in residual urine volume remaining in the bladder.12

The most compelling findings show that the combination of nettle root extract and saw palmetto extract can produce improvements similar to those of prescription benign prostatic hyperplasia medications with far fewer adverse events.6,14,15 Of particular interest, a study involving 257 elderly men with benign prostatic hyperplasia found that the combination of the extracts reduced the International Prostate Symptom Scores by 53%, improve urinary flow by 19%, and reduced residual urine volume by 44% when compared to placebo.16

In addition, repeated studies have revealed that saw palmetto, combined with nettle extract, can reduce nighttime urination by one episode per night, a substantial and significant difference.14


Regardless of the cause, symptoms of prostate enlargement that can signal prostatitis, benign prostatic hyperplasia, or prostate cancer are similar in their early stages. They include the following:

  • More frequent need to urinate
  • More urgent need to urinate
  • Decreased urine flow or dribbling
  • Frequent nighttime awakening to urinate
  • Burning with urination symptoms of prostatitis include, in addition to those of general prostate trouble:1
  • A strong and frequent urge to urinate, even when only a small amount of urine is present
  • Chills, fever, low back pain, or body aches
  • Pain in the lower abdomen, the groin area, or behind the scrotum
  • Pressure or pain in the rectum
  • Discharge from the urethra (urinary opening) during bowel movements
  • Throbbing in the genital and/or rectal area
  • Problems with sexuality and loss of drive
  • Painful ejaculation symptoms of benign prostatic hyperplasia include, in addition to those of general prostate trouble: 1
  • Hesitation or difficulty starting a urine stream
  • A weak or slow stream of urine, or just a dribble of urine
  • Frequent urination, especially at night
  • A sense of incomplete emptying of the bladder
  • Repeated stopping and starting during a single urination
  • Pushing or straining to complete bladder emptying

The symptoms of prostate cancer are often difficult to distinguish from those of benign prostatic hyperplasia. That means that men with any such symptoms should see their physicians early to allow for proper diagnosis and treatment. Annual PSA screening to detect early-stage prostate cancer is highly recommended.

Pygeum Africanum

Pygeum africanum is a plum tree from tropical Africa.17 It has been in widespread use in Central and Eastern Europe for decades and numerous human studies have demonstrated the clinical efficacy of pygeum in the management of mild to moderate benign prostatic hyperplasia.18,19 At typical doses of 100 mg per day, the extract produces significant improvements in International Prostate Symptom Scores of 38% to 46%,19reductions in frequency of nighttime urination of 32%,18 and increases in peak urinary flow rates of 16% to 19%.19 Quality of life, an important measure for this disruptive condition, was increased by about 30% in two studies.18,19

A meta-analysis of 18 randomized, controlled trials involving 1,562 men has shown similar results, with overall reduction in nocturnal urination of 19% and increased urine flow of 23%. It also showed that men who took pygeum had an important reduction in the volume of urine remaining in the bladder after urination, a major risk factor for urinary tract infections. In that analysis, men using pygeum extract were more than twice as likely as those using placebo to report an overall improvement in urinary tract symptoms.20

Additional Nutrients for Benign Prostatic Hyperplasia

Pumpkin seed. Studies have shown that supplementation with pumpkin seed led to clinically relevant reductions in the International Prostate Symptom Scores compared with placebo after three to 12 months.21,22One of these studies also showed that the combination of pumpkin seed oil and saw palmetto improved quality of life scores and showed 41.7% reduction on serum PSA levels at the end of the study when compared to baseline.22

Pollen extracts. A meta-analysis of 444 men demonstrated that rye grass pollen extract significantly improved self-rated urinary symptoms in men with benign prostatic hyperplasia. Men in this study were also more than twice as likely to report improvement in nocturnal urination compared with placebo, and no side effects were reported.23

Flaxseed. Flaxseed is a rich source of dietary lignans. In the intestine, they are converted by bacteria into other bioactive compounds, particularly enterolactone. A human study on dietary flaxseed lignan extract demonstrated significant reductions in the International Prostate Symptom Scores and improvements in quality of life in men with benign prostatic hyperplasia.24

Prostate Cancer Prevention

Prostate cancer is the second most common malignancy experienced by men,25 with more than 180,000American men diagnosed a year, according to the American Cancer Society.26

While it can be life threatening, most men do not die from prostate cancer. The five-, 10-, and 15-year survival rates for men diagnosed with prostate cancer are 99%, 98%, and 95% respectively.27 In fact, it is estimated that more than 2.9 million American men are living with the disease right now.26 In addition, it is among the most readily prevented cancers because it tends to grow very slowly and because nutritional approaches to prevention can be highly effective.17

Let’s take a look at five of the most effective nutrients against prostate cancer.


A nutrient with significant potential effects against prostate cancer is lycopene, a bright red carotenoid pigment abundant in tomatoes and other red fruits and vegetables.28-30

High consumption of lycopene has been associated with a reduced risk of developing prostate cancer—and also with a reduced risk of dying from the disease. Among men with more aggressive prostate cancers, above-average lycopene consumption was associated with a 59% reduction in the risk of dying from the disease!31

Higher blood lycopene levels have also been consistently associated with reduced prostate cancer risk.32

Additionally, lycopene inhibits the inflammatory processes that promote prostate (and many other) cancers by suppressing critical “master regulatory molecules” such as nuclear factor-kappa beta (NFkB).33

Pygeum Africanum

In addition to combating many of the symptoms of benign prostatic hyperplasia, pygeum africanum has shown early evidence of potent anticancer effects.

One study found that when mice bred to have prostate cancers were treated with pygeum extract, they had significantly lower incidence of developing the malignancy. This same study showed that when applied directly to prostate cancer cells in culture, pygeum extract had numerous benefits, including inhibiting cell proliferation, inducing apoptosis, and binding to androgen receptors used by the tumor to sustain growth.17

Another important study showed that serum from a man using pygeum extract could decrease the proliferation of prostate cells in culture and upregulated genes involved in tumor suppression.34


Most men by middle age have been offered a blood test for prostate-specific antigen (PSA), which is produced in excessive amounts by prostate cancers and can be effectively used to help identify early-stage malignancy. PSA can also elevate in response to prostatitis and benign prostate enlargement.

Lycopene, the red pigment from tomatoes and other red fruits and vegetables, is one of the few compounds convincingly demonstrated to slow the rise of PSA in men with prostate cancer.

One study showed that, for men with advanced tumors, lycopene plus removal of the testes (to deprive the tumor of growth-promoting male hormones) was superior to surgery alone, with a significant difference in PSA levels by two years after the procedure.51 Men in this study also had fewer secondary tumors, better relief from bone pain, improved urine flow, and, most importantly, an improved survival rate compared with those undergoing testes removal only.

In another study of men with prostate cancer, 10 mg of lycopene per day significantly slowed the rate of PSA rise in 70% of treated men, and in 21%, turned the rise into a decline.52

Since PSA is now known to have direct contributions to prostate cancer growth in addition to serving as a marker for the disease,43 it seems sensible for men, even without known cancers, to supplement with lycopene as a way of suppressing this important risk factor.

Three Additional Nutrients to Fight Prostate Cancer

Boswellia extract. Numerous studies on cultured prostate cancer cells have shown that boswellia extract induces tumor death by apoptosis.35-38 Other studies also show that its components may prevent tumor growth by blocking the androgen (male hormone) receptors39 and by inhibiting the formation of new blood vessels (angiogenesis), further depriving tumors of nutrients.36

Flaxseed. Studies confirmed that flaxseed supplementation lowers PSA levels and significantly reduces the proliferation of normal prostate cells and prostate cancer cells.40,41 In a clinical study, supplementation with flaxseed generated favorable reductions in tumor proliferation rates in men with prostate cancer in as little as 30 days.41

Boron. According to one study, men with the highest dietary boron intakes have a 54% lower risk of developing prostate cancer compared to those with the lowest intake.42 Boron is known to block certain growth factors necessary for tumor development, and it has also been shown to inhibit the enzymatic action of PSA, which releases those same growth factors from their transport proteins.43 In an animal study, human prostate cancers implanted in mice were smaller by 38% following low-dose boron supplementation, while serum PSA levels fell 89%. 43

Relief for Chronic Prostatitis

Chronic prostatitis is a term used to describe ongoing inflammation of the prostate gland, usually in the absence of any known infection. 1 It is often found as part of a condition known as chronic prostatitis/chronic pelvic pain syndrome, both of which are common in older men and unfortunately difficult to treat with standard medication, leaving men who suffer from this condition in considerable misery.44-46

Fortunately, studies show that rye grass pollen extract may be a viable approach to treating this challenging condition.

One early study demonstrated that men assigned to receive rye grass pollen extract showed significant improvements in reported pain and quality of life. They also showed improvements on total scores on the NIH Chronic Prostatitis Symptom Index scale, compared with placebo.47

Subsequent studies found similar results, with more supplemented subjects reporting significant improvements in quality of life and symptom scores.48,49

None of these studies identified significant side effects, which suggests that rye grass pollen is both safe and effective in the treatment of chronic prostatitis, a stubborn condition that has resisted other treatment approaches.


The human prostate is a small gland with an enormous impact on a man’s health. Most of its functions are important in reproductive activity, but problems tend to arise later in life.

The most common prostate problems include benign prostatic hyperplasia, chronic prostatitis, and prostate cancer. Treatments, when available, vary in effectiveness and carry considerable side effects.

A large handful of dietary supplements has shown real promise in reducing the impact of prostate disease. While no single supplement can provide complete coverage against potential problems, those discussed here have overlapping mechanisms of action. This suggests that, taken in combination, they can contribute to reducing the risk of prostate disease, and many have been shown to help reverse the most troubling symptoms.

Starting a comprehensive prostate health supplement regimen is the smart thing to do, even (and especially) before symptoms arise.


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  49. Iwamura H, Koie T, Soma O, et al. Eviprostat has an identical effect compared to pollen extract (Cernilton) in patients with chronic prostatitis/chronic pelvic pain syndrome: a randomized, prospective study. BMC Urol. 2015;15:120.
  50. Available at: Accessed Mach 17, 2016.
  51. Ansari MS, Gupta NP. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int. 2003;92(4):375-8; discussion 8.
  52. Zhang X, Wang Q, Neil B, et al. Effect of lycopene on androgen receptor and prostate-specific antigen velocity. Chin Med J (Engl). 2010;123(16):2231-6.

Written By:  Michael Tewson

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The type, not just the amount, of sugar consumption matters in risk of health problems

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The type of sugar you eat—and not just calorie count—may determine your risk for chronic disease. A new study is the first of its kind to compare the effects of two types of sugar on metabolic and vascular function. The paper is published ahead of print in the American Journal of Physiology—Heart and Circulatory Physiology.

Female rats were given a liquid solution of either glucose (a form of sugar found naturally in the body after carbohydrates are broken down) or fructose (sugar found in fruit and fruit juices) in addition to their normal diet of solid food. The rats received the sweetened solutions for eight weeks, roughly equivalent to a person eating large amounts of sugar for six years. The sugar-fed rats were compared with a control group that received plain drinking water in addition to their food supply.

Researchers found that although both sugar-fed groups consumed more calories than the control group, the total calorie intake of the glucose-fed rats was higher than the rats that were given fructose. Another surprising observation was that “despite this difference, only the fructose group exhibited a significant increase in final body weight,” wrote the research team.

In addition to higher weight gain, the fructose group showed more markers of vascular disease and liver damage than the glucose group. These included high triglycerides, increased liver weight, decreased fat burning in the liver (a factor that can contribute to fatty liver) and impaired relaxation of the aorta, which can affect blood pressure.

These findings suggest that an increase in the amount of calories consumed due to sweeteners is not the only factor involved in long-term health risks. The type of sugar may also play a role in increasing risk factors for heart disease, diabetes and other chronic diseases.

More information: Gemma Sangüesa et al. TYPE OF SUPPLEMENTED SIMPLE SUGAR, NOT MERELY CALORIE INTAKE, DETERMINES ADVERSE EFFECTS ON METABOLISM AND AORTIC FUNCTION IN FEMALE RATS, American Journal of Physiology – Heart and Circulatory Physiology (2016). DOI: 10.1152/ajpheart.00339.2016

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Low T & Low D: A Deadly Duo

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A new study sheds some light, albeit a disturbing illumination, on men who carry both low free testosterone and low Vitamin D levels.

The study was published in February of 2012 and consisted of 2,069 men*.  It’s findings concluded that when men were deficient in free testosterone and deficient in Vitamin D they had a 77% increase in cardiovascular-related mortality.

More disturbing, however, was the increase in non-cardiovascular deaths.  When deficient in both free testosterone and Vitamin D, the researchers concluded there was an astounding 133% increase in non-cardiovascular mortality.

The researchers conducting this study carefully adjusted for confounding factors like age, body-mass index, active smoking, physical activity, diabetes, C-reactive protein, prevalent coronary artery disease, serum calcium, and parathyroid hormone.

This new study closely resembles findings from a study of 858 US military veterans over the age of 40. The study took place over 8 years, with doctors monitoring the testosterone levels of the men in the group, and examining their accompanying health issues.  The results there showed an 88% increased risk of death among the men in the low testosterone range.  The study was published in the Archives of Internal Medicine.

In light of this new evidence, all men aged 30 years and older should begin testing immediately.  We recommend you seek out a qualified hormone physician who has been trained in testosterone restoration and hormone balancing.  Unfortunately, far too many primary care doctors do not test men’s testosterone levels, let alone their Vitamin D (25-Hydroxy) levels.  If they do, the resulting tests almost always omit estrogen levels.  And the therapy prescribed will, often times, be testosterone creams or gels, without any regard to estrogen increases or testicular atrophy.

Men concerned with low testosterone or who want to be tested should contact Boston Testosterone Partners.  Specialists in testosterone restoration, they now treat patients nationally through their numerous affiliate offices.

Boston Testosterone Partners has begun the widespread testing of men’s Vitamin D (25-Hydroxy) levels, in addition to their comprehensive hormone testing.  Where deficient, physician prescriptions for pharmaceutical grade Vitamin D are dispensed to patients.  Men are then retested 10 weeks post therapy to adjust and optimize their levels into the recommended 50-60 ng/mL range.

Boston Testosterone is uniquely positioned to quickly conduct testing for men nationwide.  If you are interested in having a National Hormone Physician order testing for you, please contact Boston Testosterone online.

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances.  With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women.  Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

*Lerchbaum E, Pilz S, Boehm BO, Grammer TB, Obermayer-Pietsch B, März W. Combination of low free testosterone and low vitamin D predicts mortality in older men referred for coronary angiography. Clin Endocrinol (Oxf). 2012 Feb 22. doi: 10.1111/j.1365-2265.2012.04371.x.

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Post-Meal Coffee Changes Metabolic Markers

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When enjoyed after a meal, coffee may increase levels of an appetite-regulating hormone, improve blood sugar levels, and boost endothelial function.

Coffee contains a number of compounds – most notably, polyphenols that numerous previous studies suggest exert beneficial effects for metabolic and cardiovascular disorders.  Japanese researchers enrolled 19 healthy men in a study in which each subject was given a test meal with a polyphenol-rich coffee drink (365 mg of chlorogenic acids), or placebo drink; subjects later crossed over to the other intervention.  Testing 3 hours after the meal revealed that the coffee polyphenol beverage lowered blood glucose significantly, and increased flow mediated dilation (FMD) – a marker of blood flow and vascular health.  As well, the coffee polyphenol beverage increased post-meal levels of an appetite-regulating hormone (GLP1).  The study authors write that: “these results suggest that coffee polyphenol consumption improves postprandial hyperglycemia and vascular endothelial function, which is associated with increased GLP-1 secretion and decreased oxidative stress in healthy humans.”

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Can wearable sensors tell when you’re sick?

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It may one day be possible to spot illness the same way many of us already track our exercise habits and sleep patterns: with wearable sensors, researchers say.

In a new study, 60 people wore devices that collected more than 250,000 measurements a day on things like heart rate, oxygen in the blood, activity levels, calories expended, sleep patterns and skin temperature.

After researchers got a baseline idea of normal readings for each person in the study, they looked for deviations from these typical patterns to see whether changes might be tied to new environmental conditions, illness, or other factors that can impact health.

The goal is a health dashboard that does for people what dashboards already do for cars, said senior study author Dr. Michael Snyder, director of the Center for Genomics and Personalized Medicine at Stanford University in California.

“Your car has 400 sensors, and dashboard lights go on when a problem occurs like the engine starts overheating or you are nearly running out of gas,” Snyder said by email.

“In the future, you will have multiple sensors relaying information to your smartphone, which will become your health dashboard,” Snyder added. “Alerts will go off with elevated heart rate over your normal level and heart beat abnormalities will be detected – these will enable early detection of disease, perhaps even before you can detect it yourself.”

Altogether, Snyder and colleagues collected almost 2 billion measurements from the study participants, who each wore between one and seven commercially available activity monitors around the clock.

Snyder was one of the participants.

On a long flight for a family vacation last year, he noticed changes in his heart rate and oxygen levels. From previous trips with sensors, he knew his oxygen levels normally dropped during flights and his heart rate increased at the start of the flight but then returned to normal.

On this particular flight, however, his numbers didn’t return to normal, and Snyder then went on to develop a fever and other signs of illness.

He had a hunch that it might be Lyme disease because he’d spent time outdoors in rural Massachusetts two weeks earlier and might have been bitten by a tick that transmitted the illness. He convinced a doctor to prescribe an antibiotic, then got tests results that confirmed a Lyme diagnosis.

For a few other participants, higher than normal readings for heart rate and skin temperature also turned out to signal a developing illness.

A few successful predictions don’t mean the idea is ready for prime time, however. More research is needed before the snapshots of illness detection in the study might translate into gadgets people can purchase and use on their own. One device tested was recalled, and another didn’t appear to work well, the authors note.

Just because people can monitor some vital signs right now on their smartphone or fitness tracker doesn’t mean they can diagnose themselves without help from a doctor, noted Satchidananda Panda of the Salk Institute for Biological Studies in La Jolla, California.

“Many health enthusiasts will like this idea and will use the gadgets judiciously,” Panda, who wasn’t involved in the study, added by email. “However, the danger lies in the vast majority of lay users who misinterpret the data.”

Because most patients only get vital signs checked at a physical or an appointment when they’re sick or something goes wrong, though, wearable sensors might help doctors do a better job of detecting the onset of disease and monitoring its progression, said Dr. Karandeep Singh, a medical researcher at the University of Michigan in Ann Arbor who wasn’t involved in the study.

“Physiological changes precede the development of symptoms for a variety of illnesses, and being able to detect these changes early may bring patients to attention much earlier when diseases are more readily treatable and potentially curable,” Singh said by email.

SOURCE: PLOS Biology, online January 12, 2017.

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Millions of people with metabolic syndrome may need more vitamin E

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New research has shown that people with metabolic syndrome need significantly more vitamin E – which could be a serious public health concern, in light of the millions of people who have this condition that’s often related to obesity.

A study just published in the American Journal of Clinical Nutrition also made it clear that conventional tests to measure vitamin E levels in the blood may have limited accuracy compared to tests made in research laboratories, to the point that conventional tests can actually mask an underlying problem.

Vitamin E – one of the more difficult micronutrients to obtain by dietary means – is an antioxidant important for cell protection. It also affects gene expression, immune function, aids in repair of wounds and the damage of atherosclerosis, is important for vision and neurologic function, and largely prevents fat from going rancid.

Nutrition surveys have estimated that 92 percent of men and 96 percent of women in the United States fail to get an adequate daily intake of vitamin E in their diet. It is found at high levels in almonds, wheat germ, various seeds and oils, and at much lower levels in some vegetables and salad greens, such as spinach and kale.

This study was done by researchers in the Linus Pauling Institute at Oregon State University and the Human Nutrition Program at The Ohio State University, as a double-blind, crossover clinical trial focusing on vitamin E levels in people with metabolic syndrome. It was supported by the National Institutes of Health, the National Dairy Council and DSM Nutrition.

“The research showed that people with metabolic syndrome need about 30-50 percent more vitamin E than those who are generally healthy,” said Maret Traber, a professor in the OSU College of Public Health and Human Sciences, and Ava Helen Pauling Professor in the Linus Pauling Institute.

“In previous work we showed that people with metabolic syndrome had lower bioavailability of vitamin E. Our current work uses a novel approach to measure how much vitamin E the body needs. This study clearly demonstrates that people with metabolic syndrome need a higher intake of this vitamin.”

More than 30 percent of the American public are obese, and more than 25 percent of the adults in the United States meet the criteria for metabolic syndrome, putting them at significantly increased risk for cardiovascular disease and type-2 diabetes – primary causes of death in the developed world.

That syndrome is defined by diagnosis of three or more of several conditions, including abdominal obesity, elevated lipids, high blood pressure, pro-inflammatory state, a pro-thrombotic state and insulin resistance or impaired glucose tolerance.

This research, for the first time, also clearly outlined a flaw with conventional approaches to measuring vitamin E.

By “labeling” vitamin E with deuterium, a stable isotope of hydrogen, scientists were able to measure the amount of the micronutrient that was eliminated by the body, compared to the intake. The advanced research laboratory tests, which are not available to the general public, showed that people with metabolic syndrome retained 30-50 percent more vitamin E than healthy people – showing that they needed it. When the body doesn’t need vitamin E, the excess is excreted.

But in the group with metabolic syndrome, even as their tissues were taking up and retaining the needed vitamin E, their blood levels by conventional measurement appeared about the same as those of a normal, healthy person.

“We’ve discovered that vitamin E levels often look normal in the blood, because this micronutrient is attracted to high cholesterol and fat,” Traber said. “So vitamin E can stay at higher levels in the circulatory system and give the illusion of adequate levels, even as tissues are deficient.

“This basically means that conventional vitamin E blood tests as they are now being done are useless.”

The findings support the conclusion that people with metabolic syndrome have higher levels of oxidative and inflammatory stress, scientists said in their conclusion, and require more antioxidants such as vitamins E as a result.

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Sermorelin-GHRP 2, A Profound Effect on Body Composition with Renewed Energy!

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Call Boston Testosterone Partners to learn more about our FDA approved Second Generation HGH releasing peptide therapy.

We are the Nation’s foremost medical experts in HGH optimization through the use of prescription Sermorelin GHRP2 & GHRP6!  Importantly, we are also the only Men’s Hormone Clinic that requires our pharmacies to send out Laboratory Analysis Reports with every Rx to every patient.

Far superior technology than any other Sermorelin product available in the US.  See the difference with BTP.


Eliminate Cellulite

Increase Energy

Increase Mood and Memory

Increase Lean Muscle Mass

Reduce Body Fat

Improve Skin Tone

Lower Blood Pressure

Improve Cholesterol levels

Improve Kidney Function


At Boston Testosterone, our state-of-the-art compounding pharmacy has focused their considerable knowledge on producing a product that delivers greater benefits to the patient at a price that is more affordable than HGH. This exciting, new product, SERMORELIN GHRP2, has proven to be much more effective and have a more profound effect on body composition.

When we’re young, our bodies produce a growth hormone releasing factor that triggers our pituitary gland to produce and release human growth hormone (hGH) in levels that are sufficient to sustain good health and vitality. However, as we age, growth hormone releasing factor declines causing a decrease in the production and secretion of pituitary hGH. This often results in a growth hormone deficiency that can erode health, diminish vigor and vitality, and lead to a host of undesirable symptoms.

A Natural, Effective, Affordable Alternative

Traditionally, adult growth hormone deficiency (AGHD) has been treated by substituting natural hGH with recombinant human growth hormone (rhGH). Now, our breakthrough product, SERMORELIN GHRP2 offers a natural, effective, and affordable alternative to recombinant human growth hormone for those suffering the symptoms of age-related growth hormone deficiency.

Developed in 1998 by Serono Laboratories, Inc., the makers of Saizen hGH, FDA approved Sermorelin is the most natural and effective treatment for AGHD. As a releasing agent, SERMORELIN GHRP2 triggers the pituitary gland to produce your own natural growth hormone. Your body regulates the level and frequency of hGH release, so you don’t experience the side effects associated with injected rhGH.

No Off Cycles! 

SERMORELIN GHRP2 requires no off-cycles. In fact, the longer you use it, the better your pituitary gland functions, more like it did when you were younger!!  In addition, SERMORELIN GHRP2 can be used to re-stimulate the natural production of human growth hormone, making it a very effective off-cycle medication for those on an injected rhGH therapy program.

At our pharmacy, we’ve combined the pituitary-supporting effects of Sermorelin with the stimulating action of GHRP-2 (Growth Hormone Releasing Peptide). GHRP-2 stimulates the pituitary gland which causes an increase in growth hormone release. In addition to amplifying your GH releasing Hormone, GHRP-2 also acts to suppress other hormones that inhibit your body’s natural growth hormone secretion. GHRP-2 also supports your central nervous system by protecting neurons, as well as, increasing strength similar to the way certain steroids in the dihydrotestosterone family do.

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Restore Your Health and Vitality!

Bottom line, restoring optimal growth hormone levels can sustain and promote youthful anatomy and physiology, thereby helping to restore the health and vitality often lost with age-related growth hormone deficiency. SERMORELIN GHRP2 not only provides the youth restoring benefits of hGH on body composition, it also helps maintain good pituitary health.

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