Low vitamin B12 levels may lead to brain shrinkage, cognitive problems

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For for more information on our therapies including B12 please contact Clinic Director Charlie Blaisdell at CBlaisdell@CoreNewEngland.com

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Clinic: 781-269-5953

Older people with low blood levels of vitamin B12 markers may be more likely to have lower brain volumes and have problems with their thinking skills, according to researchers at Rush University Medical Center.

The results of the study are published in the Sept. 27 issue of Neurology, the medical journal of the American Academy of Neurology.

Foods that come from animals, including fish, meat, especially liver, milk, eggs and poultry are usual sources of vitamin B12.

The study involved 121 older residents of the South side of Chicago who are a part of the Chicago Health and Aging Project (CHAP), which is a large, ongoing prospective Rush a biracial cohort of 10,000 subjects over the age of 65.

The 121 participants had blood drawn to measure levels of vitamin B12 and B12-related markers that can indicate a B12 deficiency. The same subjects took tests measuring their memory and other cognitive skills.

An average of four-and-a-half years later, MRI scans of the participants’ brains were taken to measure total brain volume and look for other signs of brain damage.

Having high levels of four of five markers for vitamin B12 deficiency was associated with having lower scores on the cognitive tests and smaller total brain volume.

“Our findings definitely deserve further examination,” said Christine C. Tangney, PhD, associate professor in the department of clinical nutrition at Rush University Medical Center, and lead author of the study. “It’s too early to say whether increasing vitamin B12 levels in older people through diet or supplements could prevent these problems, but it is an interesting question to explore. Findings from a British trial with B vitamin supplementation are also supportive of these outcomes.”

On the cognitive tests, the scores ranged from -2.18 to 1.42, with an average of 0.23. For each increase of one micromole per liter of homocysteine–one of the markers of B12 deficiency–the cognitive scores decreasedby 0.03 standardized units or points.

Tangney noted that the level of vitamin B12 itself in the blood was not associated with cognitive problems or loss in brain volume. She said that low vitamin B12 can be difficult to detect in older people when looking only at blood levels of the vitamin.

“Our findings lend support for the contention that poor vitamin B12 status is a potential risk factor for brain atrophy and may contribute to cognitive impairment,” said Tangney.


Other researchers at Rush involved in the study were Dr. Neelum T. Aggarwal, Hong Li, Robert S. Wilson, PhD, Dr. Denis Evans and Martha Clare Morris, ScD.

The study was supported by the National Institute on Aging.

Source: http://www.eurekalert.org/pub_releases/2011-09/rumc-lvb091911.php

Lipotropic Injections and Medical Weight loss

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Merriam-Webster Online dictionary defines the word ‘Lipotropic’ as something that promotes “the physiological utilization of fat.” In other words, lipotropic injections help your body burn fat. Lipotropics are essential for a healthy liver because they help reduce the amount of dangerous fat in that organ. Without lipotropic compounds, fat and bile could accumulate and rise to dangerous levels in your liver, putting you at risk for cirrhosis and other serious liver diseases. Scientists classify several substances as lipotropic compounds. Three lipotropic compounds in particular – Choline, Inositol and Methionine – help you lose weight.


This is an essential amino acid, meaning it cannot be produced by the body itself. Therefore, it is necessary to ensure an intake through nutrition and/or supplementation. Methionine has a fat-dissolving effect and reduces the depositing of fat in the liver. By helping prevent the accumulation of fat in the liver it ensures normal liver function, which is essential for the elimination of toxins from the body. Methionine also supports liver function by regulating glutathione supplies; glutathione is needed to help neutralize toxins in the liver. The body also needs plenty of Methionine to produce two other sulfur-containing amino acidsCysteine and Taurine, which help the body eliminate toxins, build strong, healthy tissues, and promote cardiovascular health.


Inositol benefits your body in a number of ways by transporting fat throughout your body and it also aids the neurons in your central nervous system to make sure everything is running smoothly. One major health benefit of Inositol is that when combined with Choline, they produce lecithin. Lecithin is fundamental in breaking down fats in your body and this means that it can prevent fat build ups in the cell walls of your heart, arteries and brain by breaking down the fatty deposits.  Less fat in your arteries, means lower cholesterol!

One of the most talked about Inositol benefits is how it benefits your hair. It’s a member of the B complex family which, are known to promote strong, healthier hair, and faster growth.


Choline serves various functions in our bodies. Over the past few years, there has been a rush of research, and there are now hints that Choline may be essential not only for the brain development of fetuses and infants, but may help prevent memory loss associated with aging.

Choline has been shown to protect the liver from certain types of damage, and can help reverse damage that has already occurred. Additionally, it may help lower cholesterol and homocysteine levels associated with cardiovascular disease, and may also help protect against some types of cancers.

Contact us for information on all of our therapies.

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BTP/CORE New England
Men’s Health Centers

HCG Combo with MIC Lipotropics, B1, B2, B3 & B12 at Boston Testosterone Partners

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HCG Combo with MIC Lipotropics, B1, B2, B3 & B12 methyl at www.BostonTestosterone.com.

If your doing Testosterone Creams or Gels without ancillary therapies to stimulate testicular function and modulate estradiol, your doing it wrong.

HCG Combo with MIC Lipotropics, B1, B2, B3 & B12
HCG Combo with MIC Lipotropics, B1, B2, B3 & B12

At Boston Testosterone Partners, our patients experience outstanding fat loss and energy with their Testosterone Therapy Protocols.

Why aren’t you getting the most out of your TRT? Click the “Get Started” page at Boston Testosterone Partners homepage to learn more about the BTP Method. Find out why BTP has received the Nation’s Highest Reviews in Men’s Health!

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