Gout Patients Should Be Screened for Erectile Dysfunction

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Erectile dysfunction (ED) is common and often severe in men suffering from gout, according to the results of a cross-sectional survey of men who presented to a rheumatology clinic.

“These results strongly support the proposal to screen all men with gout for the presence of ED. Increasing awareness should in turn lead to earlier medical attention and treatment for this distressing condition,” said lead author Naomi Schlesinger, MD, chief, Division of Rheumatology, and professor of medicine at Rutgers–Robert Wood Johnson Medical School, in New Brunswick, New Jersey.

The results of the study were presented here at the European League Against Rheumatism (EULAR) Congress 2014.

The most common inflammatory arthritis in men older than 40 years, gout is caused by deposits of urate crystals in the joints and is associated with uricemia. The crystals cause inflammation, pain, and swelling, and the inflammatory component of the disease is linked to risk factors for cardiovascular disease and coronary artery disease.

The cross-sectional study included 201 men aged 18 to 89 years who presented at a rheumatology clinic between August 2010 and May 2013. Of these, 83 had gout.

Participants filled out a Sexual Health Inventory in Men (SHIM) questionnaire, which evaluates the ability to have an erection, the firmness of the erection, the ability to penetrate sufficiently for sexual intercourse, and sexual satisfaction. A score of ≤21 indicates ED; a score of ≤10 indicates severe ED.

“Men don’t usually volunteer sexual complaints,” said Dr. Schlesinger. “The gout patients in our study were generally delighted and grateful that someone finally asked them about ED.”

The mean SHIM score for all participants was 16.88. Patients with gout had a mean SHIM score of 14.38 compared with 18.53 in patients without gout (P < .0001).

A significantly greater percentage of patients with gout had ED compared with patients without gout (76% vs 52%, P = .0007). Also, significantly more men with gout had severe ED vs men without gout (43% vs 30%, P = .007).

The presence of ED was significantly more frequent in gout patients aged 65 years or older, compared with men of the same age without gout (P = .0001), and was significantly more likely to be severe (P = .0002).

A multivariate analysis adjusted for age, hypertension, low-density cholesterol level, glomerular filtration rate, obesity, and depression found that the association between gout and ED was statistically significant (P = .0096).

Silent Coronary Artery Disease

 “It is estimated that 1 in 5 men who present with ED have silent coronary artery disease. A man with ED, even with no cardiac symptoms, is a cardiac patient until proven otherwise,” said Dr. Schlesinger. “Perhaps we could say that the 3 ‘EDs’ are related: endothelial dysfunction leads to erectile dysfunction leads to early death.

“Gout patients who present with ED have an increased rate of cardiovascular risk factors and concomitant silent coronary artery disease and should be evaluated,” she added.

 Maya Buch, MD, from the Leeds Institute of Rheumatology and Musculoskeletal Medicine, at the University of Leeds, United Kingdom, praised the authors of this study for providing new information on these conditions with overlapping risk factor — gout and cardiovascular disease.
 “These patients are at risk for cardiomyopathies, and there is no literature on ED and gout. We know that patients with gout have multiple comorbidities, and it’s clear that rheumatologists need to address that,” she explained.

“I was surprised at how many patients with gout have ED. In addition to treating hyperuricemia in our patients with gout, we need to pay attention to cardiovascular risk factors. I hope that this study makes doctors more receptive to evaluating patients for ED,” she added.

Dr. Schlesinger has disclosed no relevant financial relationships. Dr. Buch has received honoraria and consulting fees from AbbVie, Bristol-Myers Squibb, and Roche-Chugai and has a research grant from Pfizer, Inc.

 European League Against Rheumatism (EULAR) Congress 2014: Abstract OP0135. Presented June 13, 2014.

Written By: Alice Goodman

Article Source: http://www.medscape.com/viewarticle/826773

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Benefits of Sermorelin w/GHRP2 in the First Six Months

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Sermorelin and GHRP2 both stimulate the patient’s own pituitary gland by binding to specific receptors that increase production and secretion of endogenous Human Growth Hormone (HGH).  GHRP2 also acts as an appetite suppressant allowing for increased weight loss.

First Month

Weight loss/Body fat reduction

Vivid dreams

Better, sounder sleep

Improved stamina

Optimistic attitude

 

Second Month 

Improved muscle tone

Increased strength

Improved skin tone

Improved nail growth

Better digestion

Weight loss/Body fat reduction

Improved vision

Enhanced sexual function

 

Third Month

Improved mental process

Enhanced productivity

Faster wound healing

Hair re-growth

Increased libido

Increased muscle size

Faster recovery from muscle soreness

Reduced PMS symptoms

Greater body flexibility

Reduced pain

 

Fourth Month

Heightened improvements with all of the above

At times improvements may seem to diminish or plateau

Rejuvenation is still a process. Benefits should resume with continued improvements

 

Fifth Month

Improved weight loss and reduction of inches

Improved skin texture and appearance

Skin thickening and greater elasticity

Reduction of skin wrinkles

Thickening of hair with a shiny, healthy appearance

Continuation of improved muscle tone

 

Sixth Month

Diminished cellulite

Improved resistance to colds, flu and other illnesses

Improved eyesight

Healing of old wounds

Disappearance of pain and soreness

Improved body contour

 

Contact us today for more information on Sermorelin/ghrps

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Jane Fonda reveals testosterone is the secret behind her sex success at 73

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She has attributed her youthful looks to a healthy love life and given hope to millions by saying she had the best sex of her life at 71.

So it is something of a let down to find out that even sex symbol Jane Fonda needs artificial help.

The Barbarella star has revealed she took the male sex hormone testosterone from the age of 70 to boost her libido.

Miss Fonda said it made ‘a huge difference’.

Advising other women of a certain age how to pep up their love lives, three-times married actress, political activist and fitness guru said: ‘Here’s something I haven’t said publicly yet: I discovered testosterone about three years ago, which makes a huge difference if you want to remain sexual and your libido has dropped.

‘Use testosterone, it comes in a gel, pill or patch.’

Earlier this year, Robbie Williams shocked his legions of female fans by admitting he was injecting himself with testosterone to boost his sex drive.

Although testosterone is usually thought of as a male hormone, it is also made by women, but in much smaller amounts.

Levels drop off after the menopause, leading to some doctors prescribing testosterone alongside more traditional hormone replacement therapy.

It is relatively cheap, costing around £50 for six months’ supply and comes in patches, implants and gels.

But a reinvigorated love life can come at a cost.

Miss Fonda, now 73, and in a relationship with music producer Richard Perry, who is four years her junior, told the Sunday Telegraph: ‘I had to stop because it was giving me acne.

‘It’s one thing to have plastic surgery, but it is quite another to have adolescence acne. That is going too far.’

Two years ago, she created envy in millions of bedrooms by telling how she was having the best sex of her life, despite having had spinal surgery and boasting an artificial knee and a titanium hip.

She said: ‘How do I still look good?  I owe 30 per cent to genes, 30 per cent to good sex, 30 per cent because of sports and healthy lifestyle with proper nutrition and for the remaining ten per cent, I have to thank my plastic surgeon.

But I’m happier, the sex is better and I understand life better. I don’t want to be young again.’

More recently, she has devoted 50 pages of her new autobiography to explaining how couples can keep the passion alive long after the vigour of their youth has failed.

However, her use of testosterone has remained secret until now.

British experts welcomed the revelation.

Professor John Studd, of the London PMS and Menopause Clinic has been prescribing testosterone for women for 30 years.

He said: ‘It is not just about libido.  The benefits include more energy, more self-confidence, better mood and all of those things.’

He added that carefully balancing the dose should remove the risk of side-effects such as acne and excessive bodily or facial hair.

Dr John Stevenson chairman of the charity Women’s Health Concern, said: ‘Jane Fonda clearly thinks there should be no time limit to being sexually active, which is fine. Good for her.’

However, the Royal College of Obstetricians and Gynaecologists warns that the long-term consequences of the treatment are unknown.

THE TRUTH BEHIND TESTOSTERONE

Testosterone can be part of the hormone replacement therapy given to menopausal women.

Gels that are rubbed into the skin are the most popular.  But patches, creams and implants are also available.

Topping up levels of the hormone can give a woman in her 50s or 60s the libido of someone half her age, as well as boost energy and mood.

But too high a dose carries the risk of acne and greasy skin and hair.

‘Masculine’ side-effects such as excessive bodily and facial hair and a deepened voice are also possible.

Testosterone pills aren’t given to women but can raise cholesterol, increasing the odds of heart attacks and strokes.

The Royal College of Obstetricians and Gynaecologists urges caution when prescribing the libido-boosting treatment to women other than those who have had their ovaries removed.

It advises: ‘Testosterone replacement may be associated with adverse clinical and metabolic side effects and long-term consequences are unknown.

Written By: Fiona Macrae

Read more: http://www.dailymail.co.uk/femail/article-2028544/Jane-Fonda-reveals-testosterone-secret-sex-success-73.html#ixzz4cj0r8L4x

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Estrogen Dominance In Men

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How it is ruining your health and virility, and what you need to do to prevent It

Estrogen dominance is often thought of as a female-only disorder, however men suffer with it as well, and overexposure to estrogen-like compounds (xenoestrogens), has made it increasingly common.

Understanding Male Estrogen Dominance

The healthy range of estradiol is between 15 and 60 pg/ml. When estradiol climbs higher than that, or when testosterone levels fall too low to balance out estrogen, estrogen dominance occurs.

Estrogen Dominance Symptoms

Estrogen dominance can cause: mental fatigue, memory problems, an inability to concentrate, moodiness, irritability, emotional hypersensitivity, insomnia, unrelenting physical fatigue, depression, obesity, bone loss, back pain, headaches, and high cholesterol.

Estrogen Dominance and Your Sex Life

Estrogen dominance can cause: a loss of libido, an inability to get and/or maintain an erection, low sperm count, infertility, an inability to orgasm, and male breast enlargement.

Estrogen Dominance and Prostate Health

As estradiol levels climb, both prostate size and fibrous tissues increase. This makes it hard to urinate and increases the risk for prostate cancer and benign prostatic hyperplasia (BPH).

Four Main Causes of Estrogen Dominance in Men

Cause #1: Diet

Animal products are major estrogen dominance contributors. Non-organic produce and processed foods made from them, can also contribute to estrogen dominance because they are grown with herbicides and pesticides which mimic estrogen.

Cause #2: Excess Body Weight

Fat tissues are rich in an enzyme that converts protein into testosterone, and testosterone into estradiol; the more fat you have, the higher your estradiol levels will be. Estrogen is also stored in fat cells, so if you’re overweight you’ll need to lose excess fat cells to reverse estrogen dominance.

Cause #3: Caffeine and Alcohol

Caffeinated beverages are major estrogen dominance triggers. Alcohol is also problematic because plants used to produce alcoholic beverages contain estrogen-like compounds that mimic estrogen in the body.

Cause #4: Tight Underwear

Tight underwear forces the testicles to be squeezed up against the body, which reduces the flow of blood to the testicles and causes them to overheat. These two factors lead to an increase in estradiol and a decrease in testosterone.

Article Source: http://www.worldhealth.net/news/estrogen-dominance-men-ruining-your-health-/

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The soap chemical that could be killing your sex life is getting banned

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COULD SOMETHING IN your soap be messing with your sex life?

 When you’re in the shower and you catch a glimpse of the ingredients listed on your body wash, you usually assume they’re all good for you. For the most part, they are—but even some of those well-meaning chemicals can have unintended consequences, like the antibacterial chemical triclosan.

 

Once a popular option to put in soap, deodorant, and body wash to help kill germs, studies found that triclosan “could disrupt sex and thyroid hormones and other bodily functions,” according to CBS News. A study from researchers at the University of California, Davis also showed that the chemical can sometimes cause muscle weakness and impair muscle activity.

The Food and Drug Administration moved to ban triclosan—and 18 other antibacterial ingredients, including triclocarban, which is found in many bar soaps—ffrom being used in antibacterial soaps, with the FDA saying that soaps with the chemicals had “no scientific evidence that they are any better than plain soap and water.”

The ban will go into effect nationally in September 2017, but many companies have started to phase out any use of the chemicals in their products. The state of Minnesota didn’t feel like any of that was fast enough, so they’re banning the use of triclosan starting on Jan. 1.

Even though this chemical was once widely used, it’s one less thing you’ll have to worry about when hopping in the shower—or into bed with your girlfriend.

Written By: Matthew Jussim

Article Source: http://www.mensfitness.com/women/sex-tips/soap-chemical-could-be-killing-your-sex-life-getting-banned

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For Men, Sex Twice a Week Slashes Risk of Heart Disease

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Data from the Massachusetts Male Aging Study (US) suggests that men who have sex at least two times a week may cut their risks of heart disease by 50%.

New England Research Institute (Massachusetts, USA) researchers studied the role of sexual activity on cardiovascular disease (CVD).  Studying data from men participating in the Massachusetts Male Aging Study (USA), involving men ages 40 to 70 years, Susan A. Hall and colleagues examined sexual function variables (including erectile dysfunction) and the subsequent development of CVD.  Tracking the sexual activity of the men over a 16-year study period, the team found that a low frequency of sexual activity (once a month or less) was associated with increased risk of CVD, and that men who had sex twice a week or more were at 50% reduced risk of having a heart attack.

Article Source: http://www.worldhealth.net/news/men-sex-twice-week-slashes-risk-heart-disease/

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Decreased sexual activity, desire may lead to decline in serum testosterone in older men

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In older men, decreased sexual activity and desire, not erectile dysfunction, may cause serum testosterone to decline, a new study from Australia finds. The results will be presented Saturday March 7, at ENDO 2015, the annual meeting of the Endocrine Society, in San Diego.

“We found that over two years, men with declining serum concentrations of testosterone were more likely to develop a significant decrease in their sexual activity and sexual desire. In older men, decreased sexual activity and desire may be a cause – not an effect – of low circulating testosterone level,” said lead study author Benjumin Hsu, MPH, PhD candidate in the School of Public Health and the ANZAC Research Institute of the University of Sydney in New South Wales, Australia.

Whether decreasing sexual function is a cause or an effect of reduced androgen status in older men, or whether some other age-related factor may be involved, is not clear.

To explore the relationship between declining reproductive hormones and decreasing sexual function in older men, Hsu and his colleagues assessed men 70 years of age and above in Sydney, Australia, who took part in the Concord Health and Ageing in Men Project (CHAMP). The researchers tested the men at baseline (n=1,705) and again two years later (n=1,367).

At both visits, the participants answered questions about their sexual functions, including, “How often are you able to get and keep an erection that is firm enough for satisfactory sexual activity?”; “How many times over the last month have you had sexual activity (including intercourse and masturbation) reaching ejaculation?”; and, “How much desire for sex do you have now, compared with when you were 50?”

At both visits, the researchers also measured the men’s serum testosterone, dihydrotestosterone (DHT), estradiol (E2), and estrone (E1) by liquid chromatography-tandem mass spectrometry; and they measured the men’s sex hormone-binding globulin (SHBG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) by immunoassay.

Over two years, baseline serum testosterone, DHT, E2 and E1 did not predict decline in sexual activity, sexual desire and erectile function. By contrast, the decline in testosterone (but not in DHT, E2 or E1) over time, though less than 10%, was strongly related to decreased sexual activity and desire, but not to erectile dysfunction.

The National Health and Medical Research Council, Sydney Medical School Foundation and Ageing and Alzheimer’s Institute funded the CHAMP study.

Article Source: http://www.eurekalert.org/pub_releases/2015-03/tes-dsa030615.php

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