By Boston Testosterone Partners, Boston Massachusetts

Boston Testosterone Partners

Boston Testosterone Partners

First it was testosterone caused prostate cancer.  Now apparently it causes repeat heart attacks in men over 65.

The study getting news was a seriously flawed observational (computers only) study of VA patients, over 65, who have already had heart attacks.  No chart review of the patients was made.  There is no indication of complete patient blood testing levels.  No indication of any other medicines taken, no indication of the subjects valve disease, ejection fraction, etc., no indication of any dietary habits, lifestyle habits or activities.

And probably the most significant flaw is the fact that, in the subjects where total testosterone levels were actually available after therapy began, the average scores of the group rose from 175 to 332.  Those levels, in either case, are both considered low and well below the reference range for male total testosterone by the nation’s top diagnostic testing laboratory.  (Normal Total Testosterone Ranges for Men are 348 – 1197 per LabCorp as of March 18, 2014)

Essentially, the study is saying that the ineffective use of medical testosterone therapy which results in the continued low testosterone levels of men poses cardiovascular dangers in said high risk groups.

Moreover, the study found no risks at all in men under 65 who use testosterone therapy.

Nationally recognized endocrinology expert, Ann Cappola, MD, Chairperson of the Dept of Endocrinology at the University of Penn School of Medicine, published in the same issue as the study, acknowledged that the study group as a whole already had significant health issues (the prior heart attacks) and found “frustratingly little information” in the VA database that was used by the authors of the study.

These types of observational studies are far from the level of accuracy of a controlled clinical study.  Observational studies can conclude almost any bizarre result you wish with very little effort.

The anecdotal evidence has always been clear as well:

– Young men with high testosterone/low estrogen ratios don’t have heart attacks or get prostate cancer.

– However, older men with low testosterone/high estrogen ratios do get prostate cancer and have heart attacks.

And as more proof that this observational study is seriously flawed, in 2012, the exact same type of VA subject study (Shores and 28 investigators) found a complete opposite result.  That study, based on the same review factors, found a 39% REDUCTION in mortality risk (death) among patients treated with testosterone therapy.

The media completely ignored this positive study then, and now.

Said 17 year veteran Boston Trial Attorney last week about the class action lawsuits that are riding the coat tails of the study, “I’ve read it (the study) and seen the resulting class action ads.  The law firms are in a race with each other to get the most plaintiffs so they can be appointed class counsel and, thereafter, stand to profit from settlements.  It’s a classic money grab that uses the words may, might and maybe, in the hopes that they can establish a class and a hopeful payday from cream and gel manufacturers.  And we all understand who makes the most money in class action settlements.” said Tannous from his downtown Boston office.

The study they are using to justify the mays and maybes carries no weight or authority in a court of law.  It’s derived from faux science, it’s fundamentally flawed and flies counter to 20 years of actual data and clinical studies regarding the safety and efficacy of judiciously administered testosterone therapy.  It’s a dangerous state of affairs when misinformation can make it around the world before the truth has a chance to put it’s boots on.”

Medicine and Medical Products lawsuits play an important role in society, they remove unreasonably dangerous products from the stream of commerce and help right some wrongs.  But instead of helping society today, these actions will only cause thousands more primary care physicians to stick their heads in the sand.  It’s just more carelessness and misinformation in our cut & paste society.” said Tannous.

What Tannous refers to is the fact that, now, more primary care doctors will refuse to test and treat hormonal deficiencies.  Proper hormone balance prevents disease, promotes good physical and mental health and betters the length and quality of a man’s life.

Tannous in the legal community and The American Academy for Anti Aging (A4M), Dr. Abraham Morgentaler, Professor in the Department of Urology at Harvard University, Harvard University trained physician Dr. Richard Gaines, MD and hormone specialist Dr. Jenifer Landa, MD in the medical community have all been forced to put on the boots and explain what has been known for years in the learned medical circles.

Just as the prostate cancer myth was thoroughly debunked by Harvard University experts, so has this latest myth been discredited.

Don’t let sensational media headlines scare you.  Make informed decisions based on facts and actual clinical studies.

Contact New England’s Leading Men’s Health and Preventative Medicine Center, Boston Testosterone Partners to learn more about our Testosterone Replacement Therapy Protocols and Second Generation HGH Therapies, Sermorelin GHRP2 GHRP6.

American Academy for Anti Aging Response:

Harvard University Dr. Morganthanler’s March 4, 2014 Journal Article:

Huffington Post:

Life Extension Foundation Response:


A summary of the long term safety of testosterone therapy

December of 2013 – Journal of the American Heart Association reviewed over 150 research studies to assess the connection between testosterone and cardiovascular disease. The authors concluded that low testosterone is associated with increased rates of mortality, including cardiovascular-related mortality.The severity of disease correlated with the degree of deficiency.

(Peyman Mesbah Oskui M.D. et al. Testosterone and the Cardiovascular System: A Comprehensive Review of the Clinical Literature. Journal of the American Heart Association 2013)

Testosterone treatment resulted in a 39 percent decreased mortality risk vs. men not treated with testosterone.

(Shores MM et al. Testosterone treatment and mortality in men with low testosterone levels.  Journal of Clinical Endocrinology and Metabolism 2012)

Men with testosterone levels in the lowest quartile of sample were 40 percent more likely to die than those with higher levels. In this study, low testosterone also predicted increased risk of cardiovascular disease.

(Gail A. Laughlin et al.  Low Serum Testosterone and Mortality in Older Men. Journal of Clinical Endocrinology and Metabolism 2007)

Testosterone improves coronary artery blood-flow.

(Chou TW, Circulation, 1996, 94: 2614)

Healthy testosterone levels lower risk factors for coronary heart disease.

(Phillips GB et al. The association of hypotestosteronemia with coronary artery disease in men. Arterioscler Thromb. 1994 May;14(5):701-6 Department of Medicine, Columbia University College of Physicians and Surgeons,St. Luke’s-Roosevelt Hospital Center, New York, NY)

Elevated estrogen has the following impacts:

Elevated triglycerides and LDL cholesterol

Lowered HDL cholesterol

Elevated blood coagulation & platelet aggregation

Lowered ratio of testosterone/estrogens

Elevated arterial hypertension

Lowered blood circulation to the brain

(Portnoi AS et al, Urol Nefrol Mosk, 1992, 1-39: 6-11)

Healthy heart tissue has a 2.5 x higher testosterone concentration than skeletal muscles.

(Krieg M et al. Demonstration of a specific androgen receptor in rat heart muscle: relationship between binding, metabolism, and tissue levels of androgens. Endocrinology. 1978 Nov;103(5)

Low T linked to Hyperlipidemia (high cholesterol) and glucose intolerance (pre-diabetic).

(Gerald B, Am J Medicine, 1978, 65: 7-11)

Elevated estrogen in males increases the risk of coronary insufficiency & myocardial infarct.

(Entrican JH et al, Lancet, 1978, Sept, 487-90)


A compilation of articles with Study Citations:

Contact New England’s Leading Men’s Health and Preventative Medicine Center, Boston Testosterone Partners to learn more about our Testosterone Replacement Therapy Protocols and Second Generation HGH Therapies, Sermorelin GHRP2 GHRP6.

Boston Testosterone Partners

Core New England

920 Washington Street

Norwood, MA  02062

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