People are becoming more health conscious and are bending towards use of artificial sweeteners, especially zero calorie ones. These replacements sugars have been demonstrated to be likely to cause health changes which are associated with obesity and diabetes.
Model rats were fed diets which were high in fructose or glucose or acesulfame potassium, or aspartame; which are natural and zero calorie artificial sweeteners. Differences in concentrations of amino acids, fats, and other blood parameters observed within the animals after 3 weeks of being on the diets, specifically acesulfame potassium was found to be accumulating with in the blood and in higher concentrations damaging the blood vessel wall linings.
There has been a significant rise in diabetes and obesity despite the use of non-caloric artificial sweeteners. Researchers explain that this study shows that both artificial sweeteners and sugar have negative effects on the body which leads to diabetes and obesity, with the mechanisms for the cause of obesity differing for both.
When there was an overload of sugar machinery which handles them breaks down. Non-caloric artificial sweeteners lead to negative changes in metabolism, energy, and fat. More research is required on the subject, but results are enough to show high dietary sugars and artificial sweeteners do have negative health outcomes.
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https://www.eurekalert.org/pub_releases/2018-04/eb2-wzs041218.php
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